Use of ppd for the adjuvantation of a nucleic acid vaccine

A - Human Necessities – 61 – K

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A61K 39/39 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2652457

The present invention provides a novel adjuvant for nucleic acid vaccines, and in particular the present invention provides nucleic acid vaccines that comprise, or are administered in association with PPD. The present invention also provides methods to improve the therapeutic efficacy of nucleic acid vaccines.

La présente invention concerne un nouvel adjuvant pour des vaccins à base d'acides nucléiques, et, en particulier, la présente invention concerne des vaccins à base d'acides nucléiques qui contiennent un dérivé protéique purifié (PPD) ou sont administrés conjointement avec un PPD. La présente invention concerne également des procédés destinés à l'amélioration de l'efficacité thérapeutique de vaccins à base d'acides nucléiques.

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