Human c-ha-ras proto-oncogene transgenic rat

A - Human Necessities – 01 – K

Patent

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Details

A01K 67/027 (2006.01) A61K 49/00 (2006.01) C12N 15/85 (2006.01) C12Q 1/00 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2245494

The present invention provides a human a-Ha-ras proto-oncogene transgenic rat and the methods of the screening of many carcinogens and the screenings of promoters of carcinogenesis and preventive and inhibitory agents of tumors, and additionally enables the analysis of the carcinogenesis mechanism of a number of tumors. The rat is industrially extremely useful.

La présente invention porte sur un rat transgénique ayant le proto-oncogène humain a-Ha-ras, les méthodes de sélection de nombreux cancérogènes, la sélection de promoteurs jouant un rôle dans la cancérogenèse et des agents prévenant ou inhibant les tumeurs, et permet également l'analyse du mécanisme causant la cancérogenèse de plusieurs tumeurs. Le rat sera extrêmement utile pour l'industrie.

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