C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) C07K 14/54 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2196200
A soluble protein having IL4 and/or IL13 antagonist or partial antagonist activity comprises an IL4 mutant or variant fused to at least one human immunoglobulin constant domain or fragment thereof.
Protéine soluble ayant une activité antagoniste complète ou partielle de IL4 (interleukine 4) et/ou de IL13, qui comprend un variant ou mutant de IL4 fusionné avec au moins un domaine constant d'immunoglobuline humaine ou fragment dudit domaine.
Browne Michael Joseph
Chapman Conrad Gerald
Clinkenbeard Helen Elizabeth
Murphy Kay Elizabeth
Shatzman Allan Richard
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
Smithkline Beecham P.l.c.
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