A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/557 (2006.01) A61K 31/5575 (2006.01) C07C 405/00 (2006.01)
Patent
CA 2445651
The present invention relates to a novel cathartic composition that is useful for relieving or preventing constipation, and also for cleansing the gastrointestinal tract. The composition comprises a cathartic-inducing effective amount of halogenated bioactive lipid comprising the following partial structure (I): (See formula I) wherein B is -CH2-CH2-, -CH=CH- or -C.ident.C-; Z is(See formula II) or (See formula III) wherein R4 and R5 are hydrogen, hydroxy, halogen, lower alkyl, lower alkoxy or hydroxy(lower)alkyl, wherein R4 and R5 are not hydroxy and lower alkoxy at the same time; X1 and X2 are hydrogen, lower alkyl or halogen, and at least one of them is halogen. 2. The method as described in claim 1, wherein said halogenated bioactive lipid is the compound represented by the formula (II):
L'invention concerne une composition cathartique utile pour soulager ou prévenir la constipation, et pour nettoyer le tractus gastro-intestinal. La composition renferme une quantité efficace de lipide bioactif halogéné à effet cathartique, comportant la structure partielle ci-après. (I)
Ueno Ryuji
Kirby Eades Gale Baker
Sucampo Ag
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