Radio-opaque polymer biomaterials

Details Radio-opaque polymer biomaterials Radio-opaque polymer biomaterials

C - Chemistry, Metallurgy

07

C

C07C 229/00 (2006.01) C08G 63/00 (2006.01) C08G 63/06 (2006.01) C08G 64/12 (2006.01) C08G 65/331 (2006.01) C08G 69/44 (2006.01) C08L 69/00 (2006.01) C08L 77/04 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2308721

Iodinated and/or brominated derivatives of aromatic dihydroxy monomers are prepared and polymerized to form radio-opaque polymers. The monomers may also be copolymerized with other dihydroxy monomers. The iodinated and brominated aromatic dihydroxy monomers can be employed as radio-opacifying, biocompatible non-toxic additives for other polymeric biomaterials. Radio-opaque medical implants and drug delivery devices for implantation prepared from the polymers of the present invention are also disclosed.

Selon l'invention, on prépare des dérivés iodés et/ou bromés de monomères dihydroxy aromatiques et on les polymérise afin d'obtenir des polymères opaques aux rayons. On peut également copolymériser ces monomères avec d'autres monomères dihydroxy. On peut employer ces monomères dihydroxy aromatiques iodés et bromés en tant qu'additifs d'opacification, non toxiques, biocompatibles, destinés à d'autres biomatériaux polymères. L'invention concerne encore des implants médicaux et dispositifs d'apport de médicaments, opaques aux rayons, préparés à partir des polymères de la présente invention.

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