Benzanilides

Details Benzanilides Benzanilides

C - Chemistry, Metallurgy

07

C

167/207, 167/268

C07C 323/63 (2006.01) A61K 31/165 (2006.01) A61K 31/33 (2006.01) C07C 237/42 (2006.01) C07C 237/44 (2006.01) C07C 317/50 (2006.01) C07C 323/41 (2006.01) C07C 323/62 (2006.01) C07D 207/09 (2006.01) C07D 213/40 (2006.01) C07D 213/57 (2006.01) C07D 275/03 (2006.01) C07D 285/135 (2006.01) C07D 295/192 (2006.01) C07D 307/52 (2006.01)

Patent

CA 2026273

ABSTRACT Benzanilide derivatives of the formula: Image I wherein R1 is alkyl optionally containing double or triple bonds, and optionally interrupted by one or more hetero atoms; R2 is hydrogen, methyl, or ethyl; R3 is halogen, alkyl, -OY, -SOnY, or dimethylamino; R4 and R5 are hydrogen, alkyl or -(CH2)m-Z, wherein: (i) Z is -OCH3, -SOqCH3, -N(CH3)2 or alkanoylamino, and m is 2, 3 or 4; or (ii) Z is heterocyclyl and m is 0, 1, 2, 3, or 4; X is oxygen, -OCH2-, -SOp-, -SOpCH2- or -NR6-; R6 is hydrogen, methyl, ethyl, or acyl; Y is alkyl; and n, p and q are each 0, 1, or 2; are useful as anti-atherosclerotic agents.

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