Compositions and methods for detecting pre-cancerous...

Details Compositions and methods for detecting pre-cancerous... Compositions and methods for detecting pre-cancerous...

G - Physics

01

N

G01N 33/574 (2006.01) A61K 47/10 (2006.01) A61K 49/00 (2006.01) G01N 1/30 (2006.01) G01N 33/52 (2006.01)

Patent

CA 2725716

Presented is a method to detect precancerous states in mammalian cell and tissue samples comprising incubating a sample wit solubilized 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine (TCPP), measuring TCPP fluorescence in the sample, and categorizing the sample, and categorizing the sample as non-cancerous, precancerous or cancerous based on TCPP fluorescence, as correlated with the respective states of the cells. In conjunction with the method a detection, a novel and more efficient method of solubilizing TCPP is presented, as well as a composition comprising TCPP solubilized by this method.

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