Viral expression vectors

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/40 (2006.01) C07K 14/08 (2006.01) C12N 5/14 (2006.01) C12N 15/82 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2373026

The present invention provides nucleic acid sequences having an altered viral movement protein and 126/183kDa replicase proteins further characterized in its ability to stabilize a transgene contained in a virus that expresses the altered movement protein. The present invention also provides viral vectors expressing the altered movement protein, cells transformed with the vectors, and host plants infected by the viral vectors.

L'invention concerne des séquences d'acides nucléiques possédant une protéine de déplacement viral modifiée, ainsi que des protéines de 126/183kDa réplicase caractérisées par leur capacité à stabiliser un transgène contenu dans un virus exprimant la protéine de déplacement modifiée. Elle concerne également des vecteurs viraux exprimant cette protéine de déplacement modifiée, des cellules transformées au moyen de ces vecteurs et des plantes hôtes infectées par ces vecteurs viraux.

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