Method for early prediction of the onset of invasive cancer

Details Method for early prediction of the onset of invasive cancer Method for early prediction of the onset of invasive cancer

A - Human Necessities

61

K

A61K 49/00 (2006.01) A61B 10/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2392213

A prognostic method for early prediction of eventual development of invasive cancer comprises identifying suspect cancerous and precancerous tissue sites by applying a dye which selectively stains such sites, followed by molecular genetic analysis to determine whether the DNA of such sites exhibits allelic losses for mutation of tumor suppressor genes.

L'invention concerne un procédé de pronostic destiné au dépistage précoce d'une possible apparition d'un cancer de type envahissant, ce procédé consistant à identifier les sites tissulaires suspects, cancéreux ou précancéreux, par application d'un colorant marquant de manière sélective ces sites, puis par analyse génétique moléculaire aux fins de détermination si l'ADN de tels sites présente des pertes alléliques correspondant à une mutation des gènes suppresseurs de tumeurs.

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