Methods of screening for modulators of cell proliferation...

G - Physics – 01 – N

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G01N 33/50 (2006.01) A61K 39/395 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2387804

Described herein are methods that can be used for diagnosis and prognosis of cellular proliferation. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate cellular proliferation. Additionally, methods and molecular targets (genes and their products) for therapeutic intervention in cancers are described.

L'invention concerne des procédés qui peuvent s'utiliser pour le diagnostic et le pronostic de prolifération cellulaire. Elle concerne aussi des procédés pouvant s'utiliser pour cribler les agents candidats bioactifs pour découvrir leur capacité de moduler la prolifération cellulaire. En outre, l'invention concerne des procédés et cibles moléculaires (gènes et leurs produits) destinés à l'intervention thérapeutique lors des cancers.

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