Pressure sensitive adhesive matrix patches for transdermal...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/70 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2262693

A method of transdermally or transmucosally delivering a hydrophilic salt form of a drug with a water-based pressure sensitive hydrophobic adhesive matrix patch optionally containing a permeation enhancer is disclosed. A matrix patch (10) comprising a water-based pressure sensitive hydrophobic adhesive (14), a hydrophilic salt form of a drug, and optionally a permeation enhancer for transdermal or transmucosal delivery of the hydrophilic salt form of the drug is also disclosed.

Cette invention se rapporte à un procédé permettant d'administrer par voie transdermique ou transmuqueuse un médicament se présentant sous forme de sel hydrophile, au moyen d'un timbre adhésif hydrophobe à structure autocollante à base d'eau contenant un agent d'accentuation de la perméabilité. Cette invention se rapporte également à un timbre (10) comportant un adhésif hydrophobe à structure autocollante à base d'eau (14), un médicament se présentant sous forme de sel hydrophile et éventuellement un agent d'accentuation de la perméabilité, qui est destiné à l'administration par voie transdermique ou transmuqueuse d'un médicament se présentant sous forme de sel hydrophile.

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