Mismatch endonucleases and methods of use

C - Chemistry – Metallurgy – 12 – N

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C12N 9/16 (2006.01) C12N 9/22 (2006.01) C12N 15/10 (2006.01) C12N 15/82 (2006.01) C12P 19/34 (2006.01) C12P 21/00 (2006.01) C12Q 1/44 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2473187

We describe here restriction endonucleases and their uses. Restriction endonucleases are useful in finding single nucleotide polymorphisms. They are also useful in an in vitro method of redistributing sequence variations between non-identical polynucleotide sequences.

L'invention concerne des endonucléases de restriction et leurs applications. Les endonucléases de restriction sont utiles pour trouver des polymorphismes de nucléotide simple. Ces endonucléases de restriction peuvent également être utilisées dans une méthode de redistribution <i>in vitro</i> de variations de séquences entre des séquences polynucléotidiques non identiques.

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