Methods and compositions for treating neurological disorders

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C07H 1/00 (2006.01) C07H 21/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2504607

The present invention relates generally to the fields of neuroscience, growth factors and depression. More particularly, the present invention addresses the need in the art for methods and compositions for treating neurological disorders such as depression, anxiety, panic disorder, bi-polar disorder, insomnia, obsessive compulsive disorder, dysthymic disorder and schizophrenia. In certain embodiments, the invention relates to non-covalent binding interactions between insulin-like growth factors (IGFs) and IGF binding proteins (IGFBPs).

L'invention concerne, d'une manière générale, le domaine de la neuroscience, les facteurs de croissances et la dépression. Plus particulièrement, cette invention concerne des méthodes et des compositions permettant de traiter des troubles neurologiques, tels que la dépression, l'anxiété, les troubles paniques, les troubles bipolaires, l'insomnie, les troubles obsessionnels compulsifs, les troubles dysthimiques et la schizophrénie. Certains modes de réalisation décrits dans cette invention concernent des interactions de liaison non-covalente entre des facteurs de croissance de type insuline (IGF) et des protéines de liaison IGF (IGFBP).

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