Nanoparticles of therapeutic agents having low water solubility

A - Human Necessities – 61 – K

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Details

A61K 9/14 (2006.01) A61K 9/10 (2006.01) A61K 31/16 (2006.01) A61K 31/337 (2006.01) A61K 38/28 (2006.01) A61P 3/10 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2706933

The invention relates to a water-dispersible derivative of a therapeutic agent having a low water solubility that comprises at least one molecule of said agent covalently bonded to at least one molecule of a hydrocarbon derivative having a squalenic structure or the like. The invention further relates to corresponding nanoparticles.

La présente invention concerne un dérivé hydrodispersible d'un actif thérapeutique de faible solubilité aqueuse formé d'au moins une molécule dudit actif couplée de manière covalente à au moins une molécule d'un dérivé hydrocarboné à structure squalénique ou analogue Elle vise en outre des nanoparticules correspondantes

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