G-protein coupled receptors associated with immune response

Details G-protein coupled receptors associated with immune response G-protein coupled receptors associated with immune response

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/16 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2313450

The invention provides two human G-protein coupled receptors associated with immune response (GRIR) and polynucleotides which identify and encode GRIR. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of GRIR.

La présente invention concerne deux récepteurs humains couplés à la protéine G associés à une réaction immunitaire (GRIR), ainsi que des polynucléotides identifiant et codant les GRIR. Cette invention concerne par ailleurs des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. Enfin, cette invention concerne des procédés de traitement et de prévention des troubles associés à l'expression des GRIR.

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