Methods for lowering the level of tumor necrosis factor...

Details Methods for lowering the level of tumor necrosis factor... Methods for lowering the level of tumor necrosis factor...

C - Chemistry, Metallurgy

07

K

C07K 14/715 (2006.01) A61K 48/00 (2006.01) C12N 15/864 (2006.01)

Patent

CA 2603325

The present invention provides methods of using recombinant adeno-associated virus (rAAV) vectors encoding a tumor necrosis factor (TNF) antagonist for treatment of TNF-associated disorders or conditions such as bone loss, impairment of wound healing or bone healing, and oral buccal diseases.

Procédés d'utilisation de vecteurs de virus adéno-associés de recombinaison (rAAV) codant un antagoniste vis-à-vis du facteur TNF pour le traitement de troubles ou d'états associés au facteur TNF, du type perte osseuse, mauvaise guérison de blessure ou mauvaise guérison osseuse, et maladies oro-bucales.

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