System, substrate plate and incubation device for conducting...

Details System, substrate plate and incubation device for conducting... System, substrate plate and incubation device for conducting...

G - Physics

01

N

G01N 37/00 (2006.01) B01L 3/00 (2006.01) B01L 7/00 (2006.01) B29C 65/00 (2006.01) B29C 65/18 (2006.01) B29C 65/24 (2006.01) B29C 65/64 (2006.01) G01N 1/28 (2006.01) G01N 1/44 (2006.01) G01N 35/02 (2006.01) B29C 65/78 (2006.01)

Patent

CA 2482887

A system for conducting bioassays comprises a substrate plate with wells, and an incubation device for holding the plate. The substrate plate comprises a microplate with an array of wells arranged in rows and columns, wherein the bottom of each well is a microarray substrate having oriented flow-through channels. The incubation device comprises an incubation chamber fox holding the microplate and a cover for sealing the incubation chamber. The incubation device has a heat block with array of openings, each opening adapted to receive a well of the microplate. A sealing gasket is provided for individually sealing each well of the microplate.

L'invention concerne un système permettant de réaliser des essais biologiques, lequel système comprend une plaque de substrat dotée de cupules, et un incubateur conçu pour maintenir la plaque. La plaque de substrat comprend une microplaque dotée d'une matrice de cupules disposées en rangées et en colonnes; le fonds de chaque cupule étant un substrat de microréseaux présentant des canaux d'écoulement orientés. L'incubateur comprend une chambre d'incubation conçue pour maintenir la microplaque, et un couvercle conçu pour sceller la chambre d'incubation. L'incubateur présente un bloc chauffant doté d'un réseau d'ouvertures; chacune de ces ouvertures étant conçue pour recevoir une cupule de la microplaque. Un joint d'étanchéité est utilisé pour sceller individuellement chaque cupule de la microplaque.

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