C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01)
Patent
CA 2569511
The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inhibiting extra-cellular matrix degradation, including joint degenerative inhibiting and/or anti-inflammatory pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving extra-cellular matrix degradation in a subject.
La présente invention a trait à des procédés in vivo et in vitro, des agents et des dosages de criblage de composés pour l'inhibition de la dégradation de matrice extracellulaire, comprenant de compositions pharmaceutiques inhibitrices de la dégénérescence des articulations et/ou anti-inflammatoires, et à leur utilisation dans le traitement et/ou la prévention d'une maladie impliquant la dégradation de matrice extracellulaire chez un sujet.
Brys Reginald
Tomme Peter Herwig Maria
Vandeghinste Nick
Galapagos N.v.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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