Therapeutic agent for non-alcoholic fatty liver disease, and...

Details Therapeutic agent for non-alcoholic fatty liver disease, and... Therapeutic agent for non-alcoholic fatty liver disease, and...

A - Human Necessities

61

K

A61K 38/08 (2006.01) A61K 45/00 (2006.01) A61P 1/16 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2602716

A therapeutic agent for a non-alcoholic fatty liver disease comprising a melanin-concentrating hormone receptor antagonist as an active ingredient, which is developed based on a novel mechanism of action that a melanin- concentrating hormone receptor is involved in non-alcoholic fatty liver diseases. A method for screening a drug candidate compound for the treatment or prevention of a non-alcoholic fatty liver disease by utilizing the mechanism.

L~invention concerne un agent thérapeutique pour maladie adipeuse hépatique non alcoolique qui comprend un antagoniste du récepteur de l'hormone concentrant la mélanine comme principe actif, lequel est développé sur la base d'un nouveau mécanisme d'action par lequel un récepteur de l'hormone concentrant la mélanine est impliqué dans les maladies adipeuses hépatiques non alcooliques. L'invention concerne également une méthode pour sélectionner un composé candidat médicamenteux pour le traitement ou la prévention d'une maladie adipeuse hépatique non alcoolique utilisant le mécanisme.

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