Heterocyclic spiro-compounds as aldosterone synthase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 491/20 (2006.01) A61P 5/00 (2006.01) C07D 471/10 (2006.01) C07D 471/20 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2609660

The patent application relates to new heterocyclic compounds of the general formula (I) in which A, R, R1, R2, U, V, W, X, Y, Z, n and p have the definitions elucidated in more detail in the description, to a process for preparing them and to the use of these compounds as medicaments, particularly as aldosterone synthase inhibitors.

L'invention concerne de nouveaux composés hétérocycliques représentés par la formule générale (I) dans laquelle A, R, R1, R2, U, V, W, X, Y, Z, n et p sont définis de manière plus détaillée dans la description, leur procédé de préparation et leur utilisation comme médicaments, en particulier comme inhibiteurs de l'aldostérone synthase.

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