Use of polymer-copper complex to control interference of...

G - Physics – 01 – N

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G01N 33/52 (2006.01) C12Q 1/26 (2006.01) G01N 33/72 (2006.01)

Patent

CA 2083445

ABSTRACT This invention relates to a method of analyzing blood serum or plasma by a colormetric test in which a redox indicator is reduced or oxidized to provide a colored product the intensity of which is proportional to the concentration of a predetermined analyte, the improvement which comprises introducing a water insol- uble complex prepared from copper and a polymer con- taining multiple pendant carboxyl groups and copper which complex selectively combines with potentially interfering biological substances, for example hemo- globin or bilirubin in the blood to render such sub- stances insoluble in the blood sample.

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