Improved methods for the formation of disulphide bonds

Details Improved methods for the formation of disulphide bonds Improved methods for the formation of disulphide bonds

C - Chemistry, Metallurgy

12

N

C12N 15/10 (2006.01) C40B 40/08 (2006.01)

Patent

CA 2694364

The present invention relates to methods for the formation of inter-molecular disulphide bonds, including (poly)pep-tides/proteins, nucleic acids, vectors, host cells and bacteriophages used in these methods. Furthermore the invention relates to the use of this method for the improved display of (poly)peptides/proteins on the surface of bacteriophage particles.

La présente invention concerne des procédés permettant la formation de liaisons disulfure intermoléculaires, y compris les (poly)peptides/protéines, les acides nucléiques, les vecteurs, les cellules hôtes et les bactériophages utilisés dans ces procédés. L'invention concerne en outre l'utilisation de ce procédé en vue de l'expression améliorée de (poly)peptides/protéines à la surface de particules bactériophages.

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