Use of antibodies against the muc18 antigen

Details Use of antibodies against the muc18 antigen Use of antibodies against the muc18 antigen

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2472154

The present invention relates generally to the generation and characterization of anti-MUC18 monoclonal antibodies. The invention further relates to the use of such anti-MUC18 antibodies in the diagnosis and treatment of disorders associated with increased activity of MUC18, in particular, tumors, such as melanomas.

La présente invention concerne généralement la production et la caractérisation d'anticorps monoclonaux anti-MUC18. Elle concerne en outre l'utilisation desdits anticorps anti-MUC18 pour diagnostiquer ou traiter des troubles associés à une activité accrue de MUC18, en particulier des tumeurs telles que les mélanomes.

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