Method of promoting neuronal cell proliferation and...

A - Human Necessities – 61 – K

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Details

A61K 38/08 (2006.01) C07K 7/14 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2321164

The present invention provides methods, improved cell culture medium and kits for promoting neuronal cell proliferation and/or differentiation by growth in the presence of angiotensinogen, AI, AI analogues, AI fragments and analogues thereof, AII, AII analogues, AII fragments and analogues thereof and/or AII AT2 type 2 receptor agonists, either alone or in combination with other growth factors and cytokines.

La présente invention concerne des procédés, un bouillon de culture amélioré et des kits destinés à favoriser la prolifération et/ou la différentiation des neurones par le biais de la croissance en présence de l'angiotensinogène, d'AI, d'analogues d'AI, de fragments d'AI et de leurs analogues, d'AII, d'analogues d'AII, de fragments d'AII et de leurs analogues et/ou d'agonistes des récepteurs 2 d'AT¿2? d'AI, pris séparément ou en combinaison avec d'autres facteurs de croissance et cytokines.

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