Tetracyclic lactam derivatives and uses thereof

Details Tetracyclic lactam derivatives and uses thereof Tetracyclic lactam derivatives and uses thereof

A - Human Necessities

61

K

A61K 31/473 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 221/18 (2006.01)

Patent

CA 2556738

The present invention relates to Tetracyclic Lactam Derivatives, compositions comprising an effective amount of a Tetracyclic Lactam Derivative and methods for treating or preventing an inflammatory disease, a reperfusion injury, an ischemic condition, renal failure, diabetes, a diabetic complication, a vascular disease, reoxygenation injury resulting from organ transplantation, Parkinson's disease, or cancer, comprising administering to an animal in need thereof an effective amount of a Tetracyclic Lactam Derivative.

La présente invention concerne des dérivés de lactame tétracyclique, des compositions renfermant une dose efficace d'un dérivé de lactame tétracyclique et des méthodes de traitement ou de prévention de diverses pathologies maladies inflammatoires, lésion de reperfusion, état ischémique, défaillance rénale, diabète, complication liée au diabète, maladies vasculaires, lésion de réoxygénation par suite de transplantation d'organes, maladie de Parkinson ou cancer consistant à administrer une dose efficace d'un dérivé de lactame tétracyclique à un animal qui en a besoin.

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