Cell surface molecule-induced macrophage activation

Details Cell surface molecule-induced macrophage activation Cell surface molecule-induced macrophage activation

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 9/00 (2006.01) A61K 9/48 (2006.01) A61K 45/00 (2006.01) C07K 14/705 (2006.01) C12N 5/00 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2347928

This invention provides cells containing recombinant polynucleotides coding for cell surface molecules that, when expressed in the cell, result in rejection of the cell by the host immune system. The invention also provides methods of using such cells, and capsules for delivery of biologically active molecules to a patient.

L'invention concerne des cellules contenant des polynucléotides recombinants codant pour des molécules de surface qui, une fois exprimées dans une cellule, provoquent un rejet de cette cellule par le système immunitaire hôte. Cette invention concerne également des procédés d'utilisation de ces cellules, ainsi que des capsules permettant d'apporter des molécules biologiquement actives à un patient.

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