Light delivery catheter and pdt treatment method

Details Light delivery catheter and pdt treatment method Light delivery catheter and pdt treatment method

A - Human Necessities

61

N

A61N 5/06 (2006.01) A61B 18/22 (2006.01)

Patent

CA 2304233

A light delivery catheter (2), for use in PDT treatments, includes a hollow sheath (4) with a balloon (24) at its distal end. Target tissue (33) at a target site on a hollow body organ, such as a blood vessel, is inoculated with an appropriate photosensitizing agent. A light guide (14) extends along the sheath and has a light-radiating portion or light source (20) at its end within the balloon. The balloon is positioned at the target site and target tissue is irradiated causing destruction of the target tissue. The balloon defines perfusion channels (30) when the balloon is inflated so that during use fluid can continue passing through the blood vessel. The light irradiating the vessel wall is preferably of generally equal intensity. This can be achieved in whole or in part in several different ways.

Cathéter (2) servant à administrer de la lumière, conçu pour être mis en application dans des traitements thérapeutiques photodynamiques et comprenant une gaine creuse (4) dont l'extrémité distale est pourvue d'un ballonnet. On inocule dans le tissu ciblé (33), au niveau d'un emplacement ciblé sur un organe corporel creux, tel qu'un vaisseau sanguin, un agent approprié de photo-sensibilisation. Un guide de lumière (14) s'étend le long de la gaine et possède une partie irradiant de la lumière ou une source de lumière (20) à son extrémité à l'intérieur du ballonnet. On place ce ballonnet au niveau de l'emplacement ciblé et on irradie le tissu ciblé, ce qui provoque la destruction de ce dernier. Le ballonnet définit des canaux de perfusion (30) quand il est gonflé, de sorte qu'en utilisation, le liquide peut continuer à passer à travers le vaisseau sanguin. La lumière irradiant le vaisseau présente, de préférence, une intensité généralement égale. On peut réaliser ceci en totalité ou en partie de plusieurs façons différentes.

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