C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2500255
The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.
L'invention concerne des séquences génomiques modifiées, des oligonucléotides et/ou des oligomères PNA qui permettent de détecter l'état de méthylation de la cytosine d'ADN génomique. Cette invention se rapporte en outre à un procédé permettant de prévoir la réponse d'un sujet présentant un trouble de la prolifération des cellules des tissus mammaires, à un traitement endocrinien.
Foekens John
Harbeck Nadia
Hoefler Heinz
Koenig Thomas
Look Maxime P.
Epigenomics Ag
Heenan Blaikie Llp
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