Detection of infectious disease in a human or animal by...

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/04 (2006.01) G01N 15/14 (2006.01) G01N 33/50 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2757245

A method for performing a target analyte assay of a thin film anticoagulated blood sample, wherein the target analyte is the presence or absence of specific phagocytosis and/or binding of particles coated with a particular antigen or antigens by white blood cells present in the anticoagulated blood sample, wherein the particles are coated with the particular antigen or antigens, which antigens are similar or identical to antigens expressed by a defined pathogenic infectious agent of interest.

L'invention porte sur un procédé de réalisation d'un dosage d'analyte cible d'un échantillon de sang anticoagulé en couche mince, l'analyte cible étant la présence ou l'absence d'une phagocytose et/ou liaison spécifique de particules revêtues d'un antigène particulier ou d'antigènes particuliers par des globules blancs présents dans l'échantillon de sang anticoagulé, les particules étant revêtues du ou des antigènes particuliers, lesquels antigènes sont similaires ou identiques à des antigènes exprimés par un agent infectieux pathogène défini d'intérêt.

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