The use of mrp 8/14 levels for discrimination of individuals...

G - Physics – 01 – N

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G01N 33/68 (2006.01)

Patent

CA 2652306

The present invention relates to a method for determining the risk whether an individual showing at least one symptom of an evolving acute coronary syndrome (ACS) is suffering from an acute coronary syndrome comprising the steps of (a) measuring, preferably in vitro, the level of MRP 8/14, wherein (b) if the level of MRP 8/14 is at least increased, then the individual is at risk of suffering from an acute coronary syndrome. The invention further relates to methods for ruling out whether an individual showing at least one symptom of an evolving ACS is suffering from an ACS, for assessing whether an individual showing at least one symptom of an evolving ACS is not at risk of suffering from an ACS and to discriminate if an individual showing at least one symptom of an evolving ACS is at risk to suffer from an ACS and or has no ACS.

La présente invention concerne un procédé permettant déterminer le risque qu'un sujet présentant au moins un symptôme d'un syndrome coronarien aigu (ACS) en évolution soit atteint d'un syndrome coronarien aigu. Le procédé comporte les étapes consistant à (a) mesurer, de préférence in vitro, le taux de MRP 8/14; (b) toute augmentation du taux de MRP 8/14 signale que le sujet risque d'être atteint d'un syndrome coronarien aigu. L'invention porte, en outre, sur des procédés permettant d'exclure qu'un sujet présentant au moins un symptôme d'un ACS en évolution souffre d'un ACS, pour évaluer si un sujet présentant au moins un symptôme d'un ACS en évolution ne risque pas d'être atteint d'un ACS et pour déterminer si un sujet présentant au moins un symptôme d'un ACS en évolution risque d'être atteint d'un ACS et/ou n'a pas d'ACS.

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