Methods of treating proliferative diseases

A - Human Necessities – 61 – K

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A61K 31/429 (2006.01) A61P 35/02 (2006.01)

Patent

CA 2761940

Provided herein are methods of administering N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7- (2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, or a pharmaceutically acceptable salt or solvate thereof, to human patients, including a specific patient population. Specifically, dosing, dosing schedules or dosing regimens are provided herein. Methods of treating proliferative diseases or FLT-3 mediated diseases in humans are also provided.

La présente invention concerne des procédés d'administration de N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7- (2-morpholin-4-yl-éthoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phényl}urée, ou son sel ou solvate pharmaceutiquement acceptable, à des patients humains, notamment une population de patients spécifique. Spécifiquement, l'invention concerne la posologie, les schémas posologiques ou les régimes posologiques. L'invention concerne également des méthodes de traitement de maladies prolifératives ou de maladies médiées par FLT-3 chez l'homme.

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