A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 31/16 (2006.01) A61F 2/06 (2006.01) A61L 29/16 (2006.01) A61L 31/10 (2006.01) A61L 31/14 (2006.01) A61F 2/00 (2006.01)
Patent
CA 2504524
Methods and apparatus for treatment of vulnerable plaque provide local delivery of one or more plaque stabilizing agents. Delivery of the plaque stabilizing agents described herein stabilize vulnerable plaques at and downstream of an implantation site can reduce the occurrence of rupture of these plaques. An expandable medical device for delivering a therapeutic agent locally to a vulnerable plaque includes an implantable medical device body configured to be implanted within a coronary artery, and a therapeutic dosage of a therapeutic agent for stabilization of vulnerable plaque. The therapeutic agent is affixed in openings in the implantable medical device body in a manner such that the therapeutic agent is released to the vulnerable plaque at a therapeutic dosage and over an administration period effective to stabilize the vulnerable plaque.
L'invention concerne des procédés et des appareils permettant de traiter une plaque vulnérable destinés à distribuer localement un ou plusieurs agent(s) de stabilisation de plaque. La distribution des agents de stabilisation précités, qui permet de stabiliser des plaques vulnérables au niveau et en aval d'un site d'implantation, permet de réduire la fréquence de rupture de ces plaques. Un dispositif médical extensible utilisé pour distribuer localement un agent thérapeutique à une plaque vulnérable comprend un corps de dispositif médical implantable configuré afin d'être implanté dans une artère coronaire, et un dosage d'agent thérapeutique permettant de stabiliser la plaque vulnérable. Ledit agent thérapeutique est fixé dans des ouvertures du corps de dispositif médical implantable de sorte qu'il est libéré sur la plaque vulnérable selon un dosage thérapeutique et pendant une durée d'administration efficace pour stabiliser ladite plaque vulnérable.
Litvack Frank
Parker Theodore L.
Conor Medsystems Inc.
Deeth Williams Wall Llp
Innovational Holdings Llc
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