Chromanylurea compounds that inhibit vanilloid receptor...

C - Chemistry – Metallurgy – 07 – D

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C07D 405/12 (2006.01) A61K 31/416 (2006.01) A61K 31/4725 (2006.01) A61K 31/5377 (2006.01) A61K 31/55 (2006.01) A61P 29/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2588909

Compounds that are antagonists of the VR1 receptor, having formula (I) or a pharmaceutically acceptable salt, prodrug, or salt of a prodrug thereof, wherein A1, A2, A3, A4, R7, R8, R9, X, Y, Z, L, n, and m, are as defined herein, and are useful in disorders prevented or ameliorated by inhibiting the VR1 receptor.

Composés qui sont des antagonistes du récepteur VR1 de formule (I) ou un sel pharmaceutiquement acceptable, un promédicament ou le sel du promédicament, dans laquelle A1, A2, A3, A4, R7, R8, R9, X, Y, Z, L, n et m ont les significations données ci-avant et sont utilisés lors de troubles afin de les éviter ou des améliorer par inhibition du récepteur VR1.

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