Endogenously-formed conjugate of albumin

Details Endogenously-formed conjugate of albumin Endogenously-formed conjugate of albumin

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2577786

A conjugate formed in vivo and comprised of endogenous albumin and an amine- containing compound, such as a protein or a drug, is described. The conjugate is formed by in vivo cleavage of a polymer-dithiobenzyl-therapeutic agent conjugate to form an albumin-dithiobenzyl-therapeutic agent conjugate. The dithiol moiety of the albumin-therapeutic agent conjugate is cleaved in vivo to yield the free therapeutic agent in native form.

L'invention concerne un conjugué formé in vivo et constitué d'albumine endogène et d'un composé contenant une amine, tel qu'une protéine ou un médicament. Le conjugué est formé par clivage in vivo d'un conjugué polymère-dithiobenzyle-agent thérapeutique afin de former un conjugué albumine-dithiobenzyle-agent thérapeutique. La fraction dithiol du conjugué albumine-agent thérapeutique est clivée in vivo afin d'obtenir l'agent thérapeutique libre dans sa forme native.

Affiliated with

Also associated with

Rating

Endogenously-formed conjugate of albumin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Endogenously-formed conjugate of albumin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Endogenously-formed conjugate of albumin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1591191