C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/08 (2006.01) A61K 38/04 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61P 3/00 (2006.01) C07K 5/00 (2006.01) C07K 5/083 (2006.01) C07K 5/087 (2006.01) C07K 7/06 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2419888
The present invention refers to a compound represented by the general formula (I): and pharmaceutically acceptable salts thereof. The compounds can be used for the preparation of a medicament for the prophylaxis or treatment of a condition mediated by modulation of the dipeptidyl peptidase IV activity, wherein the condition preferably is selected from impaired glucose tolerance, diabetes mellitus, glucosuria and metabolic acidosis.
L'invention concerne un composé représenté par la formule (I), et ses sels acceptables sur le plan pharmaceutique. On peut utiliser ces composés afin de préparer un médicament prophylactique ou thérapeutique pour un état dans lequel la modulation de l'activité de dipeptidyle peptidase IV joue un rôle intermédiaire, cet état étant, de préférence, sélectionné dans la diminution de la tolérance au glucose, le diabète sucré, la glycosurie ou l'acidose métabolique.
Demuth Hans-Ulrich
Heins Jochen
Hoffmann Matthias
Hoffmann Torsten
Manhart Susanne
Macrae & Co.
Probiodrug Ag
Prosidion Limited
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