Substituted melatonin derivatives, process for their...

Details Substituted melatonin derivatives, process for their... Substituted melatonin derivatives, process for their...

A - Human Necessities

61

K

A61K 31/40 (2006.01) C07D 209/18 (2006.01)

Patent

CA 2551117

The invention provides 2 aryl substituted derivatives of melatonin. The invention further provides pharmaceutical compositions comprising such derivatives, methods for preparing such derivatives, and methods of using such derivatives to induce general anesthesia, sedation, and/or hypnotic or sleep effects in a patient, and to treat conditions affected by melatonin activity in a patient.

L'invention concerne ces dérivés substitués 2-aryle de mélatonine. Elle concerne également des compositions contenant de tels dérivés, des procédés de fabrication de ces dérivés et des méthodes d'utilisation desdits dérivés à des fins d'anesthésie, de sédation et de traitement chez un patient d'états affectés par l'activité de la mélatonine.

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