Novel cell line and screening method with the use of the same

Details Novel cell line and screening method with the use of the same Novel cell line and screening method with the use of the same

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61K 35/00 (2006.01) A61K 38/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2284133

A cloned cell line of undifferentiated mesenchymal cells capable of differentiating into chondrocytes and adipocytes and established from a normal matured animal; and a method for screening cell differentiation regulators. Specifically, a cell line capable of differentiating into chondrocytes and adipocytes and characterized by originating in a normal matured animals; a method for screening cell differentiation regulators by using the above cell line; screening kits containing the above cell line; cell differentiation regulators obtained by the above screening method; and drugs containing the above differentiation regulators.

L'invention a pour objet une lignée cellulaire clonée composée de cellules mésenchymateuses non différenciées qui sont capables de se différencier en chondrocytes et en adipocytes et qui proviennent d'un animal adulte normal, ainsi qu'un procédé de criblage des régulateurs de la différenciation cellulaire. L'invention concerne plus particulièrement une lignée cellulaire capable de se différencier en chondrocytes et en adipocytes, caractérisée en ce qu'elle provient d'un animal adulte normal; un procédé de criblage des régulateurs de la différenciation cellulaire utilisant ladite lignée cellulaire; des kits de criblage qui contiennent ladite lignée cellulaire; des régulateurs de la différenciation cellulaire obtenus par le procédé de criblage susmentionné; et des médicaments contenant lesdits régulateurs de la différenciation.

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