Methods for detecting endocrine cancer using kallikrein 13...

Details Methods for detecting endocrine cancer using kallikrein 13... Methods for detecting endocrine cancer using kallikrein 13...

G - Physics

01

N

G01N 33/574 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2497061

Kallikrein 13 constitutes a novel biomarker for diagnosis, treatment and monitoring of endocrine cancer. A method is provided for diagnosing and monitoring endocrine cancer or a predisposition to endocrine cancer, in a subject comprising detecting hK13 in a sample from the subject. Imaging methods, screening methods for test agents for inhibiting breast or ovarian cancer, and therapeutic applications based on kallikrein 13 are also described.

Kallikréine 13 constitue un nouveau marqueur biologique destiné au diagnostic, au traitement et à la surveillance du cancer du système endocrinien. La présente invention concerne une technique de diagnostic et de surveillance du cancer du système endocrinien ou d'une prédisposition d'un sujet à ce type de cancer. Cette technique consiste à détecter hK13 dans un prélèvement effectué sur le patient. Cette invention concerne aussi des techniques d'imageries, des techniques de recherche d'agent de test permettant d'inhiber un cancer du sein ou de l'ovaire, ainsi que des applications thérapeutiques à base de kallikréine 13..

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