C - Chemistry – Metallurgy – 40 – B
Patent
C - Chemistry, Metallurgy
40
B
C40B 40/08 (2006.01) C12Q 1/68 (2006.01) C40B 40/06 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2638916
Methods for identifying a subject at risk for developing AMD are disclosed, as are kits which can be used to practice the methods. The methods include identifying specific protective or risk polymorphisms or genotypes from the subject's genetic material, including polymorphisms in the BF, C2 and/or CFH genes. Microarrays and kits for use in these methods are also provided.
La présente invention concerne des procédés permettant d'identifier un sujet présentant un risque de développer une DMLA, ainsi que des kits qui peuvent être utilisés pour appliquer lesdits procédés. Les procédés selon l'invention incluent l'identification de polymorphismes ou de génotypes protecteurs ou de risque spécifiques à partir du matériel génétique du sujet, y compris des polymorphismes dans les gènes du BF, du C2 et/ou du CFH. L'invention concerne en outre des puces à ADN et des kits destinés à être utilisés dans ces procédés.
Allikmets Rando L.
Dean Michael C.
Gold Albert M.
Hageman Gregory S.
Fetherstonhaugh & Co.
The Government Of The United States Of America As Represented By
The Trustees Of Columbia University In The City Of New York
University Of Iowa Research Foundation
LandOfFree
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