Pyridones as src family sh2 domain inhibitors

Details Pyridones as src family sh2 domain inhibitors Pyridones as src family sh2 domain inhibitors

Category

C - Chemistry, Metallurgy

Subcategory

07

Subsubcategory

D

IPC codes

C07D 213/75 (2006.01) A61K 31/44 (2006.01) A61K 31/50 (2006.01) C07D 237/22 (2006.01) C07D 401/12 (2006.01) C07D 405/04 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Type

Patent

Patent number

CA 2315113

Description

This invention relates to compounds of formula (I) wherein Ring a, A, B, C, D, E, R and Q are defined herein. These compounds possess the ability to disrupt the interaction between regulatory proteins possessing one or more SH2 domains and their native ligands.

Cette invention concerne des composés de formule (I), le noyau a, A, B, C, D, E, R et Q étant définis dans le descriptif. Ces composés possèdent la capacité d'interrompre l'interaction entre des protéines régulatrices comportant un ou plusieurs domaines SH2 et leurs ligands négatifs.

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