A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/70 (2006.01) A61K 39/42 (2006.01) A61K 51/10 (2006.01) C07K 16/10 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2230116
The present invention relates to the identification and cloning of a novel neutralizing human monoclonal antibody to the Respiratoy Syncytial Virus. The invention provides such antibodies, fragments of such antibodies retaining RSV- binding ability, chimeric antibodies retaining RSV-binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Finally, the invention provides for diagnostic and therapeutic methods employing the antibodies and nucleic acids of the invention.
La présente invention concerne l'identification et le clonage d'un nouvel anticorps monoclonal neutralisant, d'origine humaine, et dirigé contre le Virus Syncytial Respiratoire (RSV). L'invention concerne de tels anticorps, des fragments de tels anticorps restant capables de liaison avec le RSV, des anticorps chimériques restant capables de liaison avec le RSV, et des compositions pharmaceutiques comportant de tels anticorps. L'invention concerne en outre, non seulement des acides nucléiques isolés codant les anticorps de l'invention, mais aussi des cellules hôtes transformées au moyen de ces acides nucléiques. L'invention concerne enfin des procédés de diagnostic et de traitement utilisant les anticorps et les acides nucléiques de l'invention.
Chanock Robert M.
Crowe James E. Jr.
Gilmour Page S.
Murphy Brian R.
Pilkington Glenn R.
Borden Ladner Gervais Llp
Depar Tment Of Health And Human Services The Government Of The United States Represented By The Secretary
Intracel Corporation
LandOfFree
Neutralizing monoclonal antibodies to respiratory syncytial... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Neutralizing monoclonal antibodies to respiratory syncytial..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Neutralizing monoclonal antibodies to respiratory syncytial... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1597312