Platform for the differentiation of cells

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/071 (2010.01) A61K 35/39 (2006.01) A61P 3/10 (2006.01) A61P 5/48 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2359821

The present invention relates to an in vitro method for islet cell expansion, which comprises the steps of: a) preparing dedifferentiated cells derived from cells in or associated with post-natal islets of Langerhans; b) expending the dedifferentiated cells; and c) inducing islet cell differentiation the expanded cells of step b) to become insulin-producing cells.

La présente invention concerne une méthode in vitro d'expansion de cellules sécrétrices d'insuline, qui consiste à: a) préparer des cellules différenciées issues de cellules présentes dans ou associées à des ilôts post-natals de Langerhans; b) expanser les cellules différenciées; et c) induire dans les cellules expansées de l'étape b) une différenciation cellulaire capable de les transformer en cellules sécrétrices d'insuline.

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