Systemic delivery of neural stem cells to treat cancer

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 38/50 (2006.01) A61P 35/00 (2006.01) C12N 5/0797 (2010.01) A61K 35/12 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2406664

The present invention relates to the field of cellular and molecular therapy with modified (genetically or growth factor engineered) and unmodified stem cells (SCs). More particularly, the invention relates to a method of systemic treatment of central nervous system (CNS) and other tumors in both intracranial/intraspinal and extracranial/extraspinal sites, using neural stem cells (NSCs), a prototype for solid organ, non-hematopoietic stem cells.

La présente invention a trait au domaine de la thérapie cellulaire et moléculaire utilisant des cellules souches modifiées (génétiquement ou par facteur de croissance) et des cellules souches non modifiées (CS). Plus particulièrement, cette invention a trait à une méthode de traitement systémique du système nerveux central (SNC) et d'autres tumeurs, à la fois dans des sites intracrâniens/rachidiens et extracrâniens/extrarachidiens, à l'aide de cellules souches neuronales (CSN), de prototype pour organe solide, et de cellules souches non hématopoïétiques.

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