Benzofuran derivatives as phosphodiesterase iv inhibitors

C - Chemistry – Metallurgy – 07 – D

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C07D 405/14 (2006.01) A61K 31/496 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2306026

Benzofuran derivatives represented by general formula (I) or pharmacologically acceptable salts thereof, wherein R1 represents lower alkyl; R2 represents hydrogen or optionally substituted lower alkyl; R3, R4, R5, and R6 are the same or different and each represents hydrogen or lower alkyl; X represents CH2 or C=O; and Y represents CH2 or NH.

Dérivés de benzofuranne de formule générale (I), ou sels acceptables sur le plan pharmaceutique desdits dérivés, dans laquelle R<1> représente alkyle inférieur, R<2> représente hydrogène ou alkyle inférieur éventuellement substitué, R<3>, R<4>, R<5> et R<6> sont identiques ou différents et chacun représente hydrogène ou alkyle inférieur, X représente CH2 ou C=O et Y représente CH2 ou NH.

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