Squaric acid derivatives as protein kinase inhibitors

Details Squaric acid derivatives as protein kinase inhibitors Squaric acid derivatives as protein kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/38 (2006.01) A61K 31/137 (2006.01) A61K 31/402 (2006.01) A61K 31/41 (2006.01) A61K 31/4418 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) C07C 225/20 (2006.01) C07D 215/14 (2006.01) C07D 217/20 (2006.01) C07D 231/12 (2006.01) C07D 233/64 (2006.01) C07D 237/08 (2006.01) C07D 239/26 (2006.01) C07D 241/12 (2006.01) C07D 295/135 (2006.01)

Patent

CA 2616682

The invention relates to compounds of formula (I), wherein R, X, R 1, R2,R3, R4 and R5 have the significances specified in claim 1, wherein said compounds are embodied in the form of CHK1- CHK2- and SGK kinase inhibitors and can be used, inter alia, for treating cancer.

L'invention concerne des composés de formule (I), dans laquelle R, X, R <SUP>1</SUP>, R<SUP>2</SUP>,R<SUP>3</SUP>, R<SUP>4</SUP> et R<SUP>5</SUP> ont les significations indiquées à la revendication 1. Ces composés sont des inhibiteurs des kinases CHK1- CHK2- et SGK- et peuvent servir, entre autres, au traitement du cancer.

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