Dimeric fusion proteins and materials and methods for...

Details Dimeric fusion proteins and materials and methods for... Dimeric fusion proteins and materials and methods for...

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2558811

Polypeptide fusions, dimeric fusion proteins, and materials and methods for making them are disclosed. One of the polypeptide fusions consists of a non- immunoglobulin polypeptide, a polypeptide linker, a dimerizing domain, and, optionally, a linking polypeptide. Another of the polypeptide fusions consists of a non-immunoglobulin polypeptide, a polypeptide linker, and a second dimerizing domain.

Cette invention concerne des fusions de polypeptide, des protéines de fusion dimères, ainsi que des matériaux et des procédés permettant de les produire. Une des fusions de polypeptide comprend un polypeptide non immunoglobuline, un lieur de polypeptide, un domaine de dimérisation et éventuellement un polypeptide de liaison. Une autre de ces fusions de polypeptide comprend un polypeptide non immunoglobuline, un lieur de polypeptide et un second domaine de dimérisation.

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