C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/42 (2006.01) A61K 31/404 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 409/06 (2006.01) C07D 413/06 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 513/04 (2006.01)
Patent
CA 2700539
The invention provides well-defined aryl and/or heteroaryl substituted indoles that are useful as sphingosine-1 -phosphate agonists or antagonists. As such, the compounds described herein are useful in treating a wide variety of disorders associated with modulation of sphingosine-1 -phosphate receptors.
La présente invention concerne des indoles substitués par des groupes aryles et/ou hétéroaryles bien définis qui sont utiles en tant d'agonistes ou antagonistes de la sphingosine-1-phosphate. Ainsi, les composés selon la présente invention sont utiles dans le traitement d'une grande variété de troubles associés à la modulation des récepteurs de la sphingosine-1 -phosphate.
Beard Richard L.
Donello John E.
Yuan Haiqing
Allergan Inc.
Gowling Lafleur Henderson Llp
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