C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 498/04 (2006.01) A61K 31/535 (2006.01) C07D 265/38 (2006.01) C07D 497/04 (2006.01) C07D 497/14 (2006.01) C07D 498/14 (2006.01)
Patent
CA 2502484
The invention concerns compounds of formula (I), wherein: W¿1? represents with the carbon atoms whereto it is bound, a phenyl group or a pyridinyl group; Z represents a group selected among a hydrogen atom, halogen, a linear or branched C¿1?-C¿6? alkyl, aryl, linear or branched C¿1?-C¿6? arylalkyl, aryloxy, linear or branched C¿1?-C¿6? arylalkoxy, hydroxy, linear or branched C¿1?-C¿6? alkoxy group; R¿1? is such as defined in the description; R¿2? represents a hydrogen atom or a group of formula -CH¿2?CH¿2?O-R¿8?; R¿3?, R¿4? represent each a hydrogen atom, a linear or branched C¿1?-C¿6? alkyl, aryl, linear or branched C¿1?-C¿6? aryalkyl group; n represents an integer between 1 and 6 inclusive. The invention is useful for preparing medicines.
Composés de formule (I) dans laquelle : Wl représente avec les atomes de carbone auxquels il est lié, un groupement phényle ou un groupement pyridinyle, Z représente un groupement choisi parmi atome d'hydrogène, halogène, groupement alkyle (C1-C6) linéaire ou ramifié, aryle, arylalkyle (C1- C6) linéaire ou ramifié, aryloxy, arylalkoxy (C1-C6) linéaire ou ramifié, hydroxy, alkoxy (C1-C6) linéaire ou ramifié, R1 est tel que défini dans la description, R2 représente un atome d'hydrogène ou un groupement de formule - CH2CH2O-R8, R3, R4 représentent chacun un atome d'hydrogène, un groupement alkyle (C1-C6) linéaire ou ramifié, aryle, aryalkyle (C1-C6) linéaire ou ramifié, n représente un entier compris entre 1 et 6 inclus. Médicaments.
Caignard Daniel-Henri
Coudert Gerard
Hickman John
Kraus-Berthier Laurence
Lepifre Franck
Les Laboratoires Servier
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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