Nnrt inhibitors

Details Nnrt inhibitors Nnrt inhibitors

C - Chemistry, Metallurgy

07

D

C07D 253/06 (2006.01) A61K 31/50 (2006.01) A61K 31/53 (2006.01) A61K 31/5395 (2006.01) A61P 31/18 (2006.01) C07D 237/04 (2006.01) C07D 253/10 (2006.01) C07D 273/04 (2006.01)

Patent

CA 2623728

The present invention provides compounds of formula (I) where R1 to R4 are as defined herein which are useful for treating or preventing an human immunodeficiency virus (HIV) infection, or treating AIDS or ARC. The invention further provides for methods of treating or preventing HIV infection with compounds according to formula (I) and compositions containing the same. The invention still further provides process for the preparation of compounds of formula (I) wherein R4 is A1 and X1 is NH or O.

La présente invention concerne des composés de formule (I) où R1 à R4 sont tels que définis ici, lesdits composés étant utiles pour le traitement ou la prévention d'une infection par le virus de l'immunodéficience humaine (VIH), ou pour le traitement du SIDA ou du syndrome associé au SIDA. L'invention concerne en outre des procédés de traitement ou de prévention d'une infection par le VIH avec des composés de formule (I) et les compositions qui les contiennent. L'invention concerne enfin des procédés de préparation de composés de formule (I) dans laquelle R4 est A1 et X1 est NH ou O.

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