A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 8/60 (2006.01) A61K 8/02 (2006.01) A61K 8/34 (2006.01) A61K 8/365 (2006.01) A61K 8/44 (2006.01) A61K 8/49 (2006.01) A61K 8/67 (2006.01) A61K 8/73 (2006.01) A61K 8/81 (2006.01) A61K 47/12 (2006.01) A61K 47/26 (2006.01) A61Q 19/00 (2006.01)
Patent
CA 2377880
The present invention relates to a liquid, substantially anhydrous eutectic mixture comprising a principal acid component, such as a hydroxy acid, and at least one other component selected from the group consisting of a carbohydrate, a polyol, an amino acid, and a carboxylic acid. The mixtures remain liquid at room temperature, are relatively non-irritating, and can be used to deliver higher levels of the principal acid than would ordinarily be possible. The invention also provides a method of making such a mixture comprising heating the component having the lowest melting point to the temperature at which it melts, dissolving the remaining component or components in the melted component, and allowing the mixture to cool.
La présente invention concerne un mélange liquide sensiblement eutectique et anhydre, qui comprend un composant acide principal, tel qu'un acide hydroxy, et au moins un autre composant sélectionné dans le groupe constitué de glucide, de polyol, d'amino acide et d'acide carboxylique. Ces mélanges restent liquide à température ambiante, ne sont relativement pas irritants, et peuvent être utilisés pour apporter des niveaux plus élevés d'acide principal que ceux qu'on pourrait obtenir normalement. Cette invention concerne aussi un procédé de préparation de ce mélange, qui consiste à chauffer le composant possédant le point de fusion le plus bas à sa température de fusion, à dissoudre le composant ou les composants restant dans ce composant fondu, et à laisser ce mélange refroidir.
Derosa Mario
Rossi Mose
E-L Management Corporation
Osler Hoskin & Harcourt Llp
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